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1

Phe27Cys polymorphism of the human delta opioid receptor predisposes cells to compromised calcium signaling

Jussi T. Tuusa, Ulla E. Petäjä-Repo

Journal:

Molecular and Cellular Biochemistry

Year:

2011

Language:

english

File:

PDF, 396 KB

english, 2011

2

Cell-based β2-adrenergic receptor–ligand binding assay using synthesized europium-labeled ligands and time-resolved fluorescence

Eija Martikkala, Mirva Lehmusto, Minna Lilja, Anita Rozwandowicz-Jansen, Jenni Lunden, Takenori Tomohiro, Pekka Hänninen, Ulla Petäjä-Repo, Harri Härmä

Journal:

Analytical Biochemistry

Year:

2009

Language:

english

File:

PDF, 388 KB

english, 2009

3

Association of the beta-1 adrenergic receptor carboxyl terminal variants with left ventricular hypertrophy among diabetic and non-diabetic survivors of acute myocardial infarction

Anna E Hakalahti, Jari M Tapanainen, Juhani M Junttila, Kari S Kaikkonen, Heikki V Huikuri, Ulla E Petäjä-Repo

Journal:

Cardiovascular Diabetology

Year:

2010

Language:

english

File:

PDF, 266 KB

english, 2010

4

Phe27Cys Polymorphism Alters the Maturation and Subcellular Localization of the Human δ Opioid Receptor

Tarja T. Leskelä, Piia M. H. Markkanen, Ilkka A. Alahuhta, Jussi T. Tuusa, Ulla E. Petäjä-Repo

Journal:

Year:

2009

Language:

english

File:

PDF, 1.11 MB

english, 2009

5

Human δ opioid receptor biogenesis is regulated via interactions with SERCA2b and calnexin

Jussi T. Tuusa, Tarja T. Leskelä, Ulla E. Petäjä-Repo

Journal:

Year:

2010

Language:

english

File:

PDF, 530 KB

english, 2010

6

Ligands act as pharmacological chaperones and increase the efficiency of delta opioid receptor maturation

Petaja-Repo, U. E.

Journal:

The EMBO Journal

Year:

2002

Language:

english

File:

PDF, 274 KB

english, 2002

7

Cys-27 Variant of Human -Opioid Receptor Modulates Maturation and Cell Surface Delivery of Phe-27 Variant via Heteromerization

Leskela, T. T., Lackman, J. J., Vierimaa, M. M., Kobayashi, H., Bouvier, M., Petaja-Repo, U. E.

Journal:

Journal of Biological Chemistry

Year:

2012

Language:

english

File:

PDF, 1.56 MB

english, 2012

8

Significance of the Extracellular Domain and the Carbohydrates of the Human Neutrophil N-Formyl Peptide Chemotactic Receptor for the Signal Transduction by the Receptor

Jari J. Remes, Ulla E. Petäjä-Repo, K.Juha Tuukkanen, Hannu J. Rajaniemi

Journal:

Experimental Cell Research

Year:

1993

File:

PDF, 727 KB

1993

9

The Endoplasmic Reticulum Ca2+-pump SERCA2b Interacts with G Protein-coupled Receptors and Enhances their Expression at the Cell Surface

Jussi T. Tuusa, Piia M.H. Markkanen, Pirjo M. Apaja, Anna E. Hakalahti, Ulla E. Petäjä-Repo

Journal:

Journal of Molecular Biology

Year:

2007

Language:

english

File:

PDF, 1.30 MB

english, 2007

10

Pharmacological chaperones: a new twist on receptor folding

Jean-Pierre Morello, Michel Bouvier, Ulla E. Petäjä-Repo, Daniel G. Bichet

Journal:

Trends in Pharmacological Sciences

Year:

2000

Language:

english

File:

PDF, 888 KB

english, 2000

11

Structure and functional significance of the carbohydrates of the LH/CG receptor

H.J. Rajaniemi, U.E. Petäjä-Repo, E.M. Pietilä

Journal:

Molecular and Cellular Endocrinology

Year:

1996

Language:

english

File:

PDF, 585 KB

english, 1996

12

Allele-specific N-glycosylation delays human surfactant protein B secretion in vitro and associates with decreased protein levels in vivo

Taponen, Saija, Huusko, Johanna M., Petäjä-Repo, Ulla E., Paananen, Reija, Guttentag, Susan H., Hallman, Mikko, Haataja, Ritva

Journal:

Pediatric Research

Year:

2013

Language:

english

File:

PDF, 987 KB

english, 2013

13

Targeting opioid receptors with pharmacological chaperones

Petäjä-Repo, Ulla E., Lackman, Jarkko J.

Journal:

Pharmacological Research

Year:

2014

Language:

english

File:

PDF, 1.85 MB

english, 2014

14

A homogeneous single-label quenching resonance energy transfer assay for a δ-opioid receptor–ligand using intact cells

Kopra, Kari, Shweta,, Martikkala, Eija, Hänninen, Pekka, Petäjä-Repo, Ulla, Härmä, Harri

Journal:

The Analyst (Royal Society of Chemistry)

Year:

2013

Language:

english

File:

PDF, 434 KB

english, 2013

15

Newly Synthesized Human Opioid Receptors Retained in the Endoplasmic Reticulum Are Retrotranslocated to the Cytosol, Deglycosylated, Ubiquitinated, and Degraded by the Proteasome

Petaja-Repo, U. E., Hogue, M., Laperriere, A., Bhalla, S., Walker, P., Bouvier, M.

Journal:

Journal of Biological Chemistry

Year:

2001

Language:

english

File:

PDF, 282 KB

english, 2001

16

Subunit interaction of human chorionic gonadotropin (hCG) with rat ovarian luteinizing hormone (LH)/CG receptor

Petäjä-Repo, Ulla E., Rajaniemi, Hannu J.

Journal:

Molecular and Cellular Endocrinology

Year:

1990

Language:

english

File:

PDF, 1.15 MB

english, 1990

17

Monoamines, thyroid hormones and energy reserves in developing capercaillie chicks (Tetrao urogallus: tetraonidae)

Saaela, S, Petäjä-Repo, U, Hissa, R

Journal:

Comparative Biochemistry and Physiology Part A: Physiology

Year:

1990

Language:

english

File:

PDF, 943 KB

english, 1990

18

Association of Calnexin with Wild Type and Mutant AVPR2 that Cause Nephrogenic Diabetes Insipidus †

Morello, Jean-Pierre, Salahpour, Ali, Petäjä-Repo, Ulla E., Laperrière, André, Lonergan, Michèle, Arthus, Marie-Françoise, Nabi, Ivan R., Bichet, Daniel G., Bouvier, Michel

Journal:

Year:

2001

Language:

english

File:

PDF, 640 KB

english, 2001

19

Covalent Cross-Linking of Radiolabeled N-Formylated Hexapeptide to its Specific Receptor on Rat and Human Neutrophils: Evidence for a ligand induced complex formation

Remes, Jari, Keinänen, Kari, Petäjä-Repo, Ulla, Rajaniemi, Hannu

Journal:

Journal of Receptor and Signal Transduction Research

Year:

1992

Language:

english

File:

PDF, 969 KB

english, 1992

20

Internalization of N-Formyl Peptide Chemotactic Receptorligand Complex by Human Neutrophils: The role of the receptor's 2–kDa external domain and carbohydrates

Remes, Jari, Petäjä-Repo, Ulla, Rajaniemi, Hannu

Journal:

Journal of Receptor and Signal Transduction Research

Year:

1994

Language:

english

File:

PDF, 766 KB

english, 1994

21

A Homogeneous Single-Label Time-Resolved Fluorescence cAMP Assay

Martikkala, E., Rozwandowicz-Jansen, A., Hanninen, P., Petaja-Repo, U., Harma, H.

Journal:

Journal of Biomolecular Screening

Year:

2011

Language:

english

File:

PDF, 1.05 MB

english, 2011

22

N-Glycan-mediated Quality Control in the Endoplasmic Reticulum Is Required for the Expression of Correctly Folded -Opioid Receptors at the Cell Surface

Markkanen, P. M. H., Petaja-Repo, U. E.

Journal:

Journal of Biological Chemistry

Year:

2008

Language:

english

File:

PDF, 1.46 MB

english, 2008

23

Opioid Receptor Pharmacological Chaperones Act by Binding and Stabilizing Newly Synthesized Receptors in the Endoplasmic Reticulum

Leskela, T. T., Markkanen, P. M. H., Pietila, E. M., Tuusa, J. T., Petaja-Repo, U. E.

Journal:

Journal of Biological Chemistry

Year:

2007

Language:

english

File:

PDF, 1.26 MB

english, 2007

24

Distinct Subcellular Localization for Constitutive and Agonist-modulated Palmitoylation of the Human Opioid Receptor

Petaja-Repo, U. E., Hogue, M., Leskela, T. T., Markkanen, P. M. H., Tuusa, J. T., Bouvier, M.

Journal:

Journal of Biological Chemistry

Year:

2006

Language:

english

File:

PDF, 1.04 MB

english, 2006

25

Export from the Endoplasmic Reticulum Represents the Limiting Step in the Maturation and Cell Surface Expression of the Human delta Opioid Receptor

Petaja-Repo, U. E.

Journal:

Journal of Biological Chemistry

Year:

2000

Language:

english

File:

PDF, 762 KB

english, 2000

26

Cysteine 27 Variant of the -Opioid Receptor Affects Amyloid Precursor Protein Processing through Altered Endocytic Trafficking

Sarajarvi, T., Tuusa, J. T., Haapasalo, A., Lackman, J. J., Sormunen, R., Helisalmi, S., Roehr, J. T., Parrado, A. R., Makinen, P., Bertram, L., Soininen, H., Tanzi, R. E., Petaja-Repo, U. E., Hiltune

Journal:

Molecular and Cellular Biology

Year:

2011

Language:

english

File:

PDF, 2.30 MB

english, 2011

27

Human 1-Adrenergic Receptor Is Subject to Constitutive and Regulated N-terminal Cleavage

Hakalahti, A. E., Vierimaa, M. M., Lilja, M. K., Kumpula, E.-P., Tuusa, J. T., Petaja-Repo, U. E.

Journal:

Journal of Biological Chemistry

Year:

2010

Language:

english

File:

PDF, 2.24 MB

english, 2010

28

Biochemical Characterization of β2-Adrenergic Receptor Dimers and Oligomers

Salahpour, A., Bonin, H., Bhalla, S., Petäjä-Repo, U., Bouvier, M.

Journal:

Biological Chemistry

Year:

2003

Language:

english

File:

PDF, 371 KB

english, 2003

29

Identification and Structural Characterization of the Neuronal Luteinizing Hormone Receptor Associated with Sensory Systems

Apaja, P. M., Harju, K. T., Aatsinki, J. T., Petaja-Repo, U. E., Rajaniemi, H. J.

Journal:

Journal of Biological Chemistry

Year:

2004

Language:

english

File:

PDF, 927 KB

english, 2004

30

Structural features of the LH/CG receptor

Metsikko, M. K., Petaja-Repo, U. E., Lakkakorpi, J. T., Rajaniemi, H. J.

Journal:

European Journal of Endocrinology

Year:

1990

Language:

english

File:

PDF, 3.21 MB

english, 1990

31

N -Glycan-dependent and -independent Quality Control of Human δ Opioid Receptor N-terminal Variants

Lackman, Jarkko J., Markkanen, Piia M. H., Hogue, Mireille, Bouvier, Michel, Petäjä-Repo, Ulla E.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 1.81 MB

english, 2014

32

Genetic Variation in δ-Opioid Receptor Associates with Increased β- and γ-Secretase Activity in the Late Stages of Alzheimer’s Disease

Sarajärvi, Timo, Marttinen, Mikael, Natunen, Teemu, Kauppinen, Tarja, Mäkinen, Petra, Helisalmi, Seppo, Laitinen, Marjo, Rauramaa, Tuomas, Leinonen, Ville, Petäjä-Repo, Ulla, Soininen, Hilkka, Haapasa

Journal:

Journal of Alzheimer's Disease

Year:

2015

Language:

english

File:

PDF, 351 KB

english, 2015

33

Expression of the Mature Luteinizing Hormone Receptor in Rodent Urogenital and Adrenal Tissues Is Developmentally Regulated at a Posttranslational Level

Apaja, Pirjo M., Aatsinki, Jyrki T., Rajaniemi, Hannu J., Petäjä-Repo, Ulla E.

Journal:

Year:

2005

Language:

english

File:

PDF, 365 KB

english, 2005

34

Significance of the Glycan Moiety of the Rat Ovarian Luteinizing Hormone/Chorionic Gonadotropin (CG) Receptor and Human CG for Receptor-Hormone Interaction*

PETÄJÄ-REPO, ULLA E., MERZ, WOLFGANG E., RAJANIEMI, HANNU J.

Journal:

Year:

1991

Language:

english

File:

PDF, 1.76 MB

english, 1991

35

Characterization of apela, a novel endogenous ligand of apelin receptor, in the adult heart

Perjés, Ábel, Kilpiö, Teemu, Ulvila, Johanna, Magga, Johanna, Alakoski, Tarja, Szabó, Zoltán, Vainio, Laura, Halmetoja, Eveliina, Vuolteenaho, Olli, Petäjä-Repo, Ulla, Szokodi, István, Kerkelä, Risto

Journal:

Basic Research in Cardiology

Year:

2016

Language:

english

File:

PDF, 771 KB

english, 2016

36

-Adrenergic Agonists Mediate Enhancement of 1-Adrenergic Receptor N-terminal Cleavage and Stabilization In Vivo and In Vitro

Hakalahti, A. E., Khan, H., Vierimaa, M. M., Pekkala, E. H., Lackman, J. J., Ulvila, J., Kerkela, R., Petaja-Repo, U. E.

Journal:

Molecular Pharmacology

Year:

2013

Language:

english

File:

PDF, 1.84 MB

english, 2013

37

Structural characterization of the carbohydrates of the rat ovarian luteinizing hormone/chorionic gonadotropin receptor

Petäjä-Repo, U E

Journal:

Biochemical Journal

Year:

1994

Language:

english

File:

PDF, 1.73 MB

english, 1994

38

Rat and human neutrophil N -formyl-peptide chemotactic receptors. Species difference in the glycosylation of similar 35-38 kDa polypeptide cores

Remes, J J, Petäjä-Repo, U E, Rajaniemi, H J

Journal:

Biochemical Journal

Year:

1991

Language:

english

File:

PDF, 1.52 MB

english, 1991

39

Significance of the carbohydrate moiety of the rat ovarian luteinizing-hormone/chorionic-gonadotropin receptor for ligand-binding specificity and signal transduction

Petäjä-Repo, U E, Merz, W E, Rajaniemi, H J

Journal:

Biochemical Journal

Year:

1993

Language:

english

File:

PDF, 1.22 MB

english, 1993

40

Allele-Specific Glycosylation of ILE131THR Variant Retards Surfactant Protein B Processing and Secretion: Basis of Predisposition to Respiratory Distress Syndrome

Huusko, J, Taponen, S, Petäjä-Repo, U E, Paananen, R, Guttentag, S H, Haataja, R, Hallman, M

Journal:

Pediatric Research

Year:

2011

Language:

english

File:

PDF, 14 KB

english, 2011

41

Site-specific O -glycosylation of N-terminal serine residues by polypeptide GalNAc-transferase 2 modulates human δ-opioid receptor turnover at the plasma membrane

Lackman, Jarkko J., Goth, Christoffer K., Halim, Adnan, Vakhrushev, Sergey Y., Clausen, Henrik, Petäjä-Repo, Ulla E.

Journal:

Cellular Signalling

Year:

2017

Language:

english

File:

PDF, 1.02 MB

english, 2017

42

N-terminal proteolytic processing of G proteiin-coupled receptor 37 (GPR37)

Mattila, Orvokki, Petäjä-Repo, Ulla

Journal:

Year:

2015

Language:

english

File:

PDF, 580 KB

english, 2015

43

The N-terminal Domain of Unknown Function (DUF959) in Collagen XVIII is Intrinsically Disordered and Highly O-glycosylated

Kaur, Inderjeet, Ruskamo, Salla, Koivunen, Jarkko, Heljasvaara, Ritva, Lackman, Jarkko J., Izzi, Valerio, Petäjä-Repo, Ulla E., Kursula, Petri, Pihlajaniemi, Taina

Journal:

Biochemical Journal

Year:

2018

Language:

english

File:

PDF, 8.41 MB

english, 2018

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